VIP 2 sizes RESEARCH USE ONLY BLACK BOX BIOTECHNOLOGY · VIP5

VIP

Also known as: Vasoactive intestinal peptide · Aviptadil
Recovery & Repair In stock Box of 10 vials 2 references

28-residue neuropeptide with potent anti-inflammatory and immunoregulatory activity.

Available sizes

SKUPer vialPack
VIP5 5 mg 10 vials / box
VIP10 10 mg 10 vials / box

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Vasoactive intestinal peptide (VIP) is a 28-amino-acid neuropeptide of the secretin/glucagon family, acting through VPAC1 and VPAC2 receptors on immune, epithelial and smooth-muscle cells.

VIP is described as one of the most potent endogenous anti-inflammatory neuropeptides: it inhibits pro-inflammatory cytokines, promotes regulatory T-cell generation and has shown protective effects in animal models of autoimmune and inflammatory disease 12.

At a glance

  • VPAC1/VPAC2 agonist; anti-inflammatory neuropeptide
  • Studied in autoimmune, pulmonary and gut-inflammation models
  • 5 mg and 10 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
Form
Lyophilized powder
Purity
HPLC-verified — Certificate of Analysis available on request
Pack size
Box of 10 vials
Storage
Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
Sequence
HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2
Formula
C147H237N43O43S
Mol. weight
3325.8 g/mol
CAS No.
37221-79-7

Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.

  1. Delgado M, Ganea D Anti-inflammatory neuropeptides: a new class of endogenous immunoregulatory agents. Brain Behav Immun. 2008;22(8):1146-51.
  2. Gonzalez-Rey E, Delgado-Maroto V, Souza Moreira L, et al. Neuropeptides as therapeutic approach to autoimmune diseases. Curr Pharm Des. 2010;16(28):3158-72.

Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.

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