Recovery
ARA-290
Also known as: Cibinetide · Helix-B surface peptide · pHBSP
Recovery & Repair In stock Box of 10 vials 1 reference
Non-erythropoietic EPO-derived peptide that engages the innate repair receptor.
Available sizes
| SKU | Per vial | Pack | |
|---|---|---|---|
| RA10 | 10 mg | 10 vials / box | |
| RA40 | 40 mg | 10 vials / box |
Order ARA-290
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ARA-290 is an 11-amino-acid peptide derived from the helix-B surface of erythropoietin. It activates the tissue-protective EPO/β-common-receptor heteromer (the 'innate repair receptor') without stimulating erythropoiesis, separating EPO's cytoprotective actions from its haematopoietic ones.
In the defining study, ARA-290 was tissue-protective in models of ischaemic stroke, renal ischaemia-reperfusion and neuropathic pain, while producing no rise in haematocrit 1.
At a glance
- Innate-repair-receptor agonist; no erythropoietic effect
- Published in PNAS; clinically studied in small-fibre neuropathy
- 10 mg and 40 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
- Form
- Lyophilized powder
- Purity
- HPLC-verified — Certificate of Analysis available on request
- Pack size
- Box of 10 vials
- Storage
- Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
- Sequence
- Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
- Formula
- C51H84N16O21
- Mol. weight
- 1257.3 g/mol
- CAS No.
- 1208243-50-8
Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.
- Brines M, Patel NS, Villa P, et al. Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. Proc Natl Acad Sci U S A. 2008;105(31):10925-30.
Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.
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