Skin
Melanotan II
MT-2 · MT-II
Cyclic superpotent α-MSH analogue with pigmentary and melanocortin-receptor activity.
10 mg
PT-141
Also known as: Bremelanotide · Vyleesi
Sexual Health & Hormonal In stock Box of 10 vials 2 references
MC4R-active melanocortin agonist — the approved compound for hypoactive sexual desire research.
Available sizes
| SKU | Per vial | Pack | |
|---|---|---|---|
| P41 | 10 mg | 10 vials / box |
Order PT-141
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PT-141 (bremelanotide) is the deamidated metabolite of Melanotan II, a cyclic heptapeptide melanocortin agonist with activity at the MC4 receptor, which governs central sexual-arousal pathways.
In the two phase 3 RECONNECT trials in premenopausal women with hypoactive sexual desire disorder (n = 1,267), bremelanotide significantly improved sexual desire and reduced associated distress versus placebo 1; a 52-week open-label extension supported long-term safety 2. It was approved by the FDA in 2019.
At a glance
- Central MC4R agonist; FDA-approved reference compound
- Phase 3 RECONNECT data in Obstet Gynecol
- 10 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
- Form
- Lyophilized powder
- Purity
- HPLC-verified — Certificate of Analysis available on request
- Pack size
- Box of 10 vials
- Storage
- Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Formula
- C50H68N14O10
- Mol. weight
- 1025.2 g/mol
- CAS No.
- 189691-06-3
Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.
- Kingsberg SA, Clayton AH, Portman D, et al. Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials. Obstet Gynecol. 2019;134(5):899-908.
- Simon JA, Kingsberg SA, Portman D, et al. Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder. Obstet Gynecol. 2019;134(5):909-917.
Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.
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