Ipamorelin 2 sizes RESEARCH USE ONLY BLACK BOX BIOTECHNOLOGY · IP5

Ipamorelin

Also known as: NNC 26-0161 · Selective GH secretagogue
Growth Hormone Axis In stock Box of 10 vials 1 reference

The first selective growth-hormone secretagogue — GH release without cortisol or prolactin.

Available sizes

SKUPer vialPack
IP5 5 mg 10 vials / box
IP10 10 mg 10 vials / box

Order Ipamorelin

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Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that stimulates GH release through the ghrelin/GHS receptor. It was identified in a Novo Nordisk programme as the first GHRP-receptor agonist whose selectivity for GH matched that of GHRH itself.

In the defining study, ipamorelin released GH with potency and efficacy comparable to GHRP-6 in rat and swine models, but — unlike GHRP-2 and GHRP-6 — did not elevate ACTH or cortisol even at doses 200-fold above the ED50, and had no effect on FSH, LH, prolactin or TSH 1.

At a glance

  • GHS-R agonist with no ACTH/cortisol/prolactin release reported
  • Original pharmacology published in Eur J Endocrinol
  • 5 mg and 10 mg vials; also in CJC and tesamorelin blends
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
Form
Lyophilized powder
Purity
HPLC-verified — Certificate of Analysis available on request
Pack size
Box of 10 vials
Storage
Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2
Formula
C38H49N9O5
Mol. weight
711.9 g/mol
CAS No.
170851-70-4

Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.

  1. Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61.

Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.

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