Longevity
Humanin
Also known as: HN · MT-RNR2-derived peptide
Longevity & Mitochondrial In stock Box of 10 vials 1 reference
24-residue mitochondrial-derived peptide identified as a neuronal survival factor.
Available sizes
| SKU | Per vial | Pack | |
|---|---|---|---|
| HUM10 | 20 mg | 10 vials / box |
Order Humanin
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Humanin is a 24-amino-acid peptide encoded in the mitochondrial 16S rRNA gene. It was discovered as a rescue factor in a screen of surviving neurons from an Alzheimer's-disease brain.
In the discovery study, humanin abolished neuronal cell death induced by a wide spectrum of familial Alzheimer's-disease genes and amyloid-β, establishing it as the first mitochondrial-derived cytoprotective peptide 1.
At a glance
- Mitochondrial-derived neuroprotective peptide
- Published in PNAS; studied in neurodegeneration and metabolic models
- 20 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
- Form
- Lyophilized powder
- Purity
- HPLC-verified — Certificate of Analysis available on request
- Pack size
- Box of 10 vials
- Storage
- Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
- Sequence
- Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
- Formula
- C119H204N34O32S2
- Mol. weight
- 2687.3 g/mol
Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.
- Hashimoto Y, Niikura T, Tajima H, et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. Proc Natl Acad Sci U S A. 2001;98(11):6336-41.
Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.
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