Pinealon 2 sizes RESEARCH USE ONLY BLACK BOX BIOTECHNOLOGY · PI10

Pinealon

Also known as: EDR peptide · Glu-Asp-Arg
Cognitive & Sleep In stock Box of 10 vials 2 references

Khavinson tripeptide bioregulator studied in neuronal gene expression and neuroprotection.

Available sizes

SKUPer vialPack
PI10 10 mg 10 vials / box
P20 20 mg 10 vials / box

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Pinealon is the synthetic tripeptide Glu-Asp-Arg (EDR), one of the short 'peptide bioregulators' developed by the St Petersburg Institute of Bioregulation and Gerontology. Short peptides of this class are proposed to enter the nucleus and modulate gene expression directly.

EDR has been reported to regulate gene expression and protein synthesis in neuronal models, with proposed epigenetic mechanisms 1, and to show neuroprotective activity in vitro 2.

At a glance

  • Tripeptide bioregulator (Khavinson series)
  • Studied in neuronal differentiation and oxidative-stress models
  • 10 mg and 20 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
Form
Lyophilized powder
Purity
HPLC-verified — Certificate of Analysis available on request
Pack size
Box of 10 vials
Storage
Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
Sequence
Glu-Asp-Arg
Formula
C15H26N6O8
Mol. weight
418.4 g/mol

Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.

  1. Khavinson V, Linkova N, Kozhevnikova E, et al. EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease. Molecules. 2020;26(1).
  2. Kozina LS, Arutiunian AV, Stvolinskiĭ SL, et al. [Biological activity of regulatory peptides in model experiments in vitro]. Adv Gerontol. 2008;21(1):68-73.

Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.

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